Pig model for post- surgical adhesion (peritoneal cavity)

A midline laparotomy is performed in order to expose the cecum. A surface on the peritoneum and on the cecum is gently abraded. The abdominal sidewall is sutured in order to create an ischemic area. Talc powder is spread on the abraded surfaces of cecum and peritoneum. Few days after the procedure the abdomen is opened carefully and cecum- peritoneum procedure is exposed and evaluated.

The advantage of the pig’s adhesions model is the organ size that are compatible with human organs size.  This model is an aggressive model for postsurgical adhesions suitable for evaluations of surgical anti- adhesion products.

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