Background: Generations of investigators have attempted to achieve compression bowel anastomosis
by a sutureless device, providing temporary support to the tissue and facilitating the natural healing process. The biocompatibility of nickel–titanium alloy has made it attractive for use in medical implants and devices, and several studies have described the creation of a side-to-side compression anastomosis in colon surgery with a nickel–titanium clip. We evaluated the feasibility and safety of a newly designed gun for applying a nickel–titanium compression anastomosis ring (CAR) to create an end-to-end colorectal anastomosis in a porcine model.